UCSD BICD 140 Winter 2013
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Dendritic cells - innate or adaptive

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Dendritic cells - innate or adaptive Empty Dendritic cells - innate or adaptive

Post  111 Mon Jan 28, 2013 12:37 am

Are Dendritic cells part of innate or adaptive immunity?
I know they are the bridge from innate to active adaptive
(carries antigen to lymph to be recognized by Tcells)

on lecture1 page 63, slide 44; the list does not include DC in innate
while lecture1 page 78, slide 53; dendritic cells are parenthesis in adaptive
but on lecture1 page 86, slide 61 its under innate

Thanks!

111
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Post  k1elder Mon Jan 28, 2013 4:58 am

The book has them listed in the innate section. I think it's because they are present in all body tissues and aren't specific to any one pathogen, which are hallmarks of adaptive immunity. According to the text, "their unique function is to act as cellular messengers that are sent to call up an adaptive immune response when it is needed". Basically, they are the bridge between innate and adaptive immunity (according to my TA). Smile

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Post  TA_1 Mon Jan 28, 2013 9:35 pm

k1elder is correct. Dentritic cells are at function innate, but bridge to the adaptive immunity, which is why it was in parentheses.

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